Effect of enalapril therapy on ventilatory pulmonary function tests in hypertensive patients.

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dc.contributor.authorSabir, Men_US
dc.contributor.authorTinna, V Ken_US
dc.contributor.authorRastogi, Aen_US
dc.contributor.authorAgarwal, R Pen_US
dc.date.accessioned1998-04-29en_US
dc.date.accessioned2009-05-31T05:13:26Z
dc.date.available1998-04-29en_US
dc.date.available2009-05-31T05:13:26Z
dc.date.issued1998-04-29en_US
dc.description.abstractFifty newly diagnosed nonsmoker patients suffering from mild to moderate hypertension (diastolic BP 90 to 114 mmHg), randomly selected and not having respiratory or other systemic diseases which may affect pulmonary functions were subjected to thorough interrogation and clinical examination. Twenty five normal age and sex matched healthy volunteers served as control. All patients and controls were subjected to ventilatory pulmonary function tests (VPFT), done by computerized spirometer. Hypertensive patients were put on oral enalapril, doses were titrated and maintained on 2.5 to 10 mg once daily. Twenty percent of the total hypertensive patients reported mild to moderate dry cough and was more frequently observed among females (27%). Significant decline was observed in MEF 50% and MEF 25% of vital capacity values (p 0.0204 and 0.0001) after 10 days of enalapril therapy. These two VPFT parameters showed significantly higher decline among patients who developed cough as compared to patients who did not develop cough. Decline in VPFT parameters were directly related to doses of enalapril.en_US
dc.description.affiliationDepartment of Medicine, Respiratory Section, Sardar Patel Medical College, Bikaner-334 003.en_US
dc.identifier.citationSabir M, Tinna VK, Rastogi A, Agarwal RP. Effect of enalapril therapy on ventilatory pulmonary function tests in hypertensive patients. Journal of the Association of Physicians of India. 1998 Apr; 46(4): 355-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/95400
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntihypertensive Agents --administration & dosageen_US
dc.subject.meshEnalapril --administration & dosageen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypertension --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrognosisen_US
dc.subject.meshReference Valuesen_US
dc.subject.meshRespiratory Function Testsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleEffect of enalapril therapy on ventilatory pulmonary function tests in hypertensive patients.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeControlled Clinical Trialen_US
dc.typeJournal Articleen_US
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