Red baby syndrome a new disease due to parvovirus B-19 observed in Kerala.

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dc.contributor.authorSasidharan, C Ken_US
dc.contributor.authorSugathan, Pen_US
dc.contributor.authorMampilly, Neenaen_US
dc.contributor.authorAgarwal, Rameshen_US
dc.contributor.authorKhare, Shashien_US
dc.contributor.authorLal, Shiven_US
dc.contributor.authorJayaram Paniker, C Ken_US
dc.date.accessioned2009-03-25en_US
dc.date.accessioned2009-05-30T13:48:51Z
dc.date.available2009-03-25en_US
dc.date.available2009-05-30T13:48:51Z
dc.date.issued2009-03-25en_US
dc.description.abstractRed Baby Syndrome is a new disease seen in infants and young children. Dramatic onset of clinical symptoms with high intensity, short duration and lack of similarity with other cutaneous lesions makes it distinct. Of 50 such patients studied over a period of 5 years, half were below one year of age. Abrupt onset of high fever and generalized erythema involving the entire skin, which is swollen and tender is characteristic. These children were highly irritable and had paradoxical cry when cuddled. Rapid resolution of symptoms occurred in 7-10 days with extensive desquamation. Routine investigations were normal, C-reactive protein was raised only in 10 patients. Human Parvo virus B-19 IgM antibodies were positive in 15 out of 24 patients. Real time polymerase chain reaction was positive for human parvovirus B 19 DNA in one. Histopathological changes in the skin biopsy showed post infectious vascular injury pattern.en_US
dc.description.affiliationBaby Memorial Hospital, Calicut, India. cksasidharan@gmail.comen_US
dc.identifier.citationSasidharan CK, Sugathan P, Mampilly N, Agarwal R, Khare S, Lal S, Jayaram Paniker CK. Red baby syndrome a new disease due to parvovirus B-19 observed in Kerala. Indian Journal of Pediatrics. 2009 Mar; 76(3): 309-12en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/82055
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAntibodies, Viral --blood
dc.subject.meshAntigens, Viral --immunology
dc.subject.meshC-Reactive Protein --metabolism
dc.subject.meshChild, Preschool
dc.subject.meshDNA, Viral --analysis
dc.subject.meshErythema --genetics
dc.subject.meshErythema --immunology
dc.subject.meshErythema --pathology
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshIndia --epidemiology
dc.subject.meshInfant
dc.subject.meshInfant, Newborn
dc.subject.meshMale
dc.subject.meshParvoviridae Infections --genetics
dc.subject.meshParvoviridae Infections --pathology
dc.subject.meshParvoviridae Infections --virology
dc.subject.meshParvovirus B19, Human --genetics
dc.subject.meshParvovirus B19, Human --immunology
dc.subject.meshParvovirus B19, Human --isolation & purification
dc.subject.meshPolymerase Chain Reaction
dc.subject.meshSkin --pathology
dc.subject.meshSkin --virology
dc.subject.meshSyndrome
dc.titleRed baby syndrome a new disease due to parvovirus B-19 observed in Kerala.en_US
dc.typeJournal Articleen_US
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