Histopathological and immunological studies in a cohort of balanitis xerotica obliterans.

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dc.contributor.authorDatta, Cen_US
dc.contributor.authorDutta, S Ken_US
dc.contributor.authorChaudhuri, Aen_US
dc.date.accessioned1993-06-01en_US
dc.date.accessioned2009-05-31T15:52:30Z
dc.date.available1993-06-01en_US
dc.date.available2009-05-31T15:52:30Z
dc.date.issued1993-06-01en_US
dc.description.abstractBalanitis xerotica obliterans consisting of 52 cases had been studied in the present series. This disease entity is an insidious sclerosing disease of unknown aetiology, affecting mainly the skin and mucous membrane of glans, prepuce and sometimes the fossa navicularis urethrae or even terminal urethra. Atrophic white patches on external genitalia and obstructive uropathy are two common presenting features. It has been classified as local form of lichen sclerosus et atrophicus. Poor local hygiene, circumcision and association of auto-immune diseases like vitiligo are responsible as suggested in this study. Routine tests detected associated cystitis in 8 cases, haematuria in 4 cases, non-reactive VDRL in all cases and impaired glucose tolerance in 5 cases. Immunoglobulin profile (39 cases) showed altered pattern, suggesting some chronic antigenic stimulation. Out of 33 cases where biopsy done, histologically proved typical balanitis xerotica obliterans was found in 19 cases. Malignant change was noted in one case only. Circumcision and dilatation offered temporary relief.en_US
dc.description.affiliationDepartment of Pathology and Bacteriology, RG Kar Medical College, Calcutta.en_US
dc.identifier.citationDatta C, Dutta SK, Chaudhuri A. Histopathological and immunological studies in a cohort of balanitis xerotica obliterans. Journal of the Indian Medical Association. 1993 Jun; 91(6): 146-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/103855
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBalanitis --immunologyen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshHematuria --complicationsen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshUrinary Tract Infections --complicationsen_US
dc.titleHistopathological and immunological studies in a cohort of balanitis xerotica obliterans.en_US
dc.typeJournal Articleen_US
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