Ichthyosiform mycosis fungoides with alopecia and atypical membranous nephropathy.
| dc.contributor.author | Zhou, Qiang | |
| dc.contributor.author | Zhu, Kejian | |
| dc.contributor.author | Yu, Haiyan | |
| dc.contributor.author | Cheng, Hao | |
| dc.date.accessioned | 2012-08-29T05:20:28Z | |
| dc.date.available | 2012-08-29T05:20:28Z | |
| dc.date.issued | 2011-03 | |
| dc.description.abstract | We describe here a rare case of variant of mycosis fungoides (MF): ichthyosiform MF with alopecia and atypical membranous nephropathy. The diagnosis was made based on the following findings: generalized ichthyosis-like eruption, alopecia, enlarged superficial lymph nodes, proteinuria, and hematuria, the histological features of the skin biopsy from both ichthyotic and alopecic lesions with immunohistochemical staining, and the renal biopsy examination with immunofluorescence. The histological examination of ichthyotic and alopecic lesions displayed a predominant infiltration of atypical lymphocytes in the upper dermis with the characteristics of epidermotropism and folliculotropism. Immunohistochemical studies demonstrated that most infiltrated atypical lymphocytes were CD3, CD4, and CD45RO positive, whereas negative for CD5, CD7, CD20, CD30, and CD56. A renal biopsy examination revealed atypical membranous nephropathy with deposition of immunoglobulin G (IgG), IgM, IgA, C1q, and C3. In this case atypical membranous nephropathy was involved, which is very uncommon and has never been presented in the literature to date. Although ichthyosiform MF usually features a relatively favorable course, diffuse alopecia and the renal involvement in this case might indicate aggressive disease and poor prognosis. | en_US |
| dc.identifier.citation | Zhou Qiang, Zhu Kejian, Yu Haiyan, Cheng Hao. Ichthyosiform mycosis fungoides with alopecia and atypical membranous nephropathy. Indian Journal of Dermatology, Venereology and Leprology. 2011 Mar-Apr; 77(2): 180-183. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/140804 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ijdvl.com/article.asp?issn=0378-6323;year=2011;volume=77;issue=2;spage=180;epage=183;aulast=Zhou | en_US |
| dc.subject | Ichthyosiform mycosis fungoides | en_US |
| dc.subject | nephropathy | en_US |
| dc.subject | alopecia | en_US |
| dc.title | Ichthyosiform mycosis fungoides with alopecia and atypical membranous nephropathy. | en_US |
| dc.type | Article | en_US |