Anti-fungal potentials of extracellular metabolites of Western Ghats isolated Streptomyces sp. NII 1006 against moulds and yeasts.

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dc.contributor.authorJayamurthy, Himani
dc.contributor.authorSajna, Kuttavan Valappil
dc.contributor.authorDastagar, Syed G
dc.contributor.authorPandey, Ashok
dc.date.accessioned2014-12-15T04:46:48Z
dc.date.available2014-12-15T04:46:48Z
dc.date.issued2014-11
dc.description.abstractRealization of hazardious effects of chemical fungicides has led to an interest in the usage of biocontrol agents. The present study, therefore, evaluates the biocontrol efficacy of Western Ghats (India) soil bacterial isolates. A potential strain NII 1006 was evaluated for its antagonistic property against a diverse range of moulds and yeasts. The strain was characterized morphologically, biochemically and molecularly, which revealed the isolate belonged to Streptomyces genus. Organic solvent extracts of NII 1006 culture filtrates inhibited the growth of the test pathogens indicating that growth suppression was due to extracellular anti-fungal metabolites present in the culture filtrates. The strain produced extracellular chitinase enzyme in addition to some stable partially purified anti-fungal compounds. Morphological changes such as hyphae degradation into debris and abnormal shapes were observed in test fungi and yeast grown on potato dextrose broth that contained the NII 1006 culture filtrate. The cell free supernatant has a tolerance to wide range of pH, temperature and enzymes such as lipase and protease. The biocontrol potential of NII 1006 strain may be correlated significantly with their ability to produce antibiotics as well as extracellular hydrolytic enzymes particularly chitinolytic enzyme.en_US
dc.identifier.citationJayamurthy Himani, Sajna Kuttavan Valappil, Dastagar Syed G, Pandey Ashok. Anti-fungal potentials of extracellular metabolites of Western Ghats isolated Streptomyces sp. NII 1006 against moulds and yeasts. Indian Journal of Experimental Biology. 2014 Nov; 52(11): 1138-1146.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/153804
dc.language.isoenen_US
dc.source.urihttps://nopr.niscair.res.in/handle/123456789/29756en_US
dc.subjectAnti-fungal activityen_US
dc.subjectBiocontrolen_US
dc.subjectExtracellular anti-fungal metabolitesen_US
dc.subjectStreptomycesen_US
dc.subject.meshAcetates
dc.subject.meshAntifungal Agents --isolation & purification
dc.subject.meshAntifungal Agents --pharmacology
dc.subject.meshCarbon --metabolism
dc.subject.meshChitinase --isolation & purification
dc.subject.meshChitinase --pharmacology
dc.subject.meshChloroform
dc.subject.meshCulture Media, Conditioned --pharmacology
dc.subject.meshDrug Evaluation, Preclinical
dc.subject.meshFungi --drug effects
dc.subject.meshGlucans --metabolism
dc.subject.meshGlycoside Hydrolases --isolation & purification
dc.subject.meshGlycoside Hydrolases --pharmacology
dc.subject.meshHexanes
dc.subject.meshHydrogen-Ion Concentration
dc.subject.meshHyphae --drug effects
dc.subject.meshIndia
dc.subject.meshNitrogen --metabolism
dc.subject.meshPlant Extracts --pharmacology
dc.subject.meshPlant Proteins --isolation & purification
dc.subject.meshPlant Proteins --pharmacology
dc.subject.meshSoil Microbiology
dc.subject.meshSolvents
dc.subject.meshStreptomyces --chemistry
dc.subject.meshStreptomyces --enzymology
dc.subject.meshStreptomyces --isolation & purification
dc.subject.meshYeasts --drug effects
dc.titleAnti-fungal potentials of extracellular metabolites of Western Ghats isolated Streptomyces sp. NII 1006 against moulds and yeasts.en_US
dc.typeArticleen_US
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