Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema

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dc.contributor.authorSaurabh, Ken_US
dc.contributor.authorRoy, Ren_US
dc.contributor.authorGoel, Sen_US
dc.date.accessioned2020-04-10T02:05:56Z
dc.date.available2020-04-10T02:05:56Z
dc.date.issued2020-01
dc.description.abstractPurpose: The aim of this study is to assess the ability of multicolour imaging (MCI) to detect foveal cysts in diabetic macular edema (DME) and compare it with conventional color fundus photography (CFP) and foveal autofluorescence (FAF) pattern. Methods: It was a retrospective review of 112 eyes of 84 DME patients with central foveal thickness ?250 ? who underwent MCI, CFP and shortwave autofluorescence imaging. MCI was performed with Sepctralis spectral domain optical coherence tomography (SDOCT) (Heidelberg Engineering, Germany). Results: 97 (86.6%) eyes had cystoid increased autofluorescence (cystoid iFAF), 9 (8%) had spot iFAF and 6 (5.35%) had irregular decreased FAF (dFAF). Among eyes with cystoid iFAF, OCT detected DME cysts in 93 (95.6%) eyes, MCI in 75 (77.3%) and CFP in 5 (5.15%) eyes. In all these eyes, the location of cysts on OCT and MCI corresponded with the location of cystoid iFAF, whereas none of the eyes with cyst seen on CFP correlated with the location of cystoid iFAF. Conclusion: MCI was superior to CFP in detecting DME cysts at fovea. It also correlated with hyperautofluorescence pattern in these eyes. MCI may have a potential role in diabetic retinopathy screening by segregating eyes with DME which would require treatment. Our findings need to be further validated in a larger and prospective study design.en_US
dc.identifier.affiliationsDepartment of Vitreo Retina, Kamalnayan Bajaj Sankara Nethralaya, Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Vitreo Retina, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, Indiaen_US
dc.identifier.citationSaurabh K, Roy R, Goel S. Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema. Indian Journal of Ophthalmology. 2020 Jan; 68(1): 141-144en_US
dc.identifier.issn0301-4738
dc.identifier.issn1998-3689
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/197727
dc.languageenen_US
dc.publisherAll India Ophthalmological Societyen_US
dc.relation.issuenumber1en_US
dc.relation.volume68en_US
dc.source.urihttps://dx.doi.org/10.4103/ijo.IJO_608_19en_US
dc.subjectAutofluorescence imagingen_US
dc.subjectcolor fundus photoen_US
dc.subjectdiabetic macular edemaen_US
dc.subjectmulticolour imagingen_US
dc.subjectoptical coherence tomographyen_US
dc.titleCorrelation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edemaen_US
dc.typeJournal Articleen_US
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