Genetic engineering and dental caries.

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dc.contributor.authorAgarwal, Shipraen_US
dc.contributor.authorPandit, I Ken_US
dc.contributor.authorSrivastava, Nikhilen_US
dc.contributor.authorGugnani, Neerajen_US
dc.date.accessioned2009-05-28T07:44:02Z
dc.date.available2009-05-28T07:44:02Z
dc.date.issued2003-10-27en_US
dc.description.abstractDental caries, a multifactorial disease requires four principle factor: the host, the microflora, the substrate & time for its occurrence and can be prevented or managed by elimination/modification of either of the above factors. The conventional preventive measure being followed for long time for the dental caries are not successful to the desirable extent due to their non avaibailaballity in the rural areas, lack of awareness & inaccessibility of dental services. Therefore, the focus has now been shifted to submicroscopic level to ensure that these measures can be reached to the farthest areas & each & every member of the population is benefitted. Few of the measures taken are. i) Genetically modifying the S. Mutans: ii) Searching The antagonist peptides to work against the specific enzyme system (Glucosyltransferase) of S. Mutans. iii) Changing the oral environment by those Genetically modified organisms that will produce bases (instead of acids) & these bases provides a milieu favoring remineralization. This paper discusses various ways in which genetically modified strains of microogranisms or genetically modified strains of microogranisms of genetically modified foods can help in the prevention of caries.en_US
dc.description.affiliationDepartment of Pedodontics and Preventive Dentistry, DAVO Dental College and Hospital, Yamunanagar, Haryana--135001.en_US
dc.identifier.citationAgarwal S, Pandit IK, Srivastava N, Gugnani N. Genetic engineering and dental caries. Indian Journal of Dental Research. 2003 Oct-Dec; 14(4): 284-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51590
dc.language.isoengen_US
dc.source.urihttps://www.ijdr.inen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDental Caries --prevention & controlen_US
dc.subject.meshFood, Genetically Modifieden_US
dc.subject.meshGenetic Engineeringen_US
dc.subject.meshGlycosyltransferases --geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshOrganisms, Genetically Modifieden_US
dc.subject.meshStreptococcus mutans --enzymologyen_US
dc.titleGenetic engineering and dental caries.en_US
dc.typeJournal Articleen_US
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