Post-metaphase mitotic events in cells treated with dinitrophenol.

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dc.contributor.authorGhosh, Sen_US
dc.contributor.authorPaweletz, Nen_US
dc.contributor.authorArmas-Portela, Ren_US
dc.date.accessioned2009-05-28T11:20:57Z
dc.date.available2009-05-28T11:20:57Z
dc.date.issued1989-04-01en_US
dc.description.abstractThe sequence of post-metaphase mitotic events, such as anaphase movement A and B, chromosome decondensation, nuclear envelope reformation and cytokinesis, has been studied in 2,4-initrophenol (DNP)-treated HeLa cells. The effects of DNP were found to be dose dependent and at concentrations higher than 3 mM, both anaphase A and B movements were totally and nearly instantaneously arrested. It could be shown that cytokinesis did not depend on the completion of anaphase movements. This was also true for nuclear envelope reformation which could take place even around condensed chromosomes arrested in anaphase. The post-metaphase mitotic events do not follow a strict causal sequence, but they can be dissociated from each other in anaphase-arrested cells.en_US
dc.identifier.citationGhosh S, Paweletz N, Armas-Portela R. Post-metaphase mitotic events in cells treated with dinitrophenol. Indian Journal of Experimental Biology. 1989 Apr; 27(4): 317-23en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56590
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.mesh2,4-Dinitrophenolen_US
dc.subject.meshAnaphase --drug effectsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCell Division --drug effectsen_US
dc.subject.meshChromosomes --drug effectsen_US
dc.subject.meshDinitrophenols --pharmacologyen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshHela Cellsen_US
dc.subject.meshHumansen_US
dc.subject.meshMetaphase --drug effectsen_US
dc.subject.meshMicroscopy, Electronen_US
dc.subject.meshMicrotubules --ultrastructureen_US
dc.subject.meshMitosis --drug effectsen_US
dc.subject.meshNuclear Envelope --drug effectsen_US
dc.titlePost-metaphase mitotic events in cells treated with dinitrophenol.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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