Solitary Fibrous Tumor of the Pleura: A Case Report
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2009-12-22
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Thai Journal of Tuberculosis Chest Diseases and Critical Care
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Abstract: Makanut S, Tscheikuna J, Suthinont P, Thongcharoen P. Solitary fibrous tumor of the pleura: a casereport. Thai J Tuberc Chest Dis Crit Care 2009; 30: 63-71.Faculty of Medicine, Siriraj Hospital, Mahidol UniversitySolitary fibrous tumors of the pleura are rare tumors arising from submesothelial mesenchymal tissue ofthe pleura. Most of the tumors have benign clinical behavior with satisfactory outcome if resected completely.Some of the tumors are malignant and eventually lead to death through local recurrence or metastatic disease.Patients with the tumors had various clinical features, ranging from no symptoms, local symptoms such asdyspnea, cough and chest pain, and systemic symptoms such as clubbing and hypoglycemia. We report a caseof a 30 year-old female patient with solitary fibrous tumors of the pleura. At presentation she had nonproductivecough, dyspnea and weight loss for 4 months. Chest radiography revealed a well-circumscribed large homogenous,pleural based extrapulmonary mass at left hemithorax. Ultrasound-guided biopsy of the pleural massshowed benign fibrous lesion markedly positive with CD34 and negative for smooth muscle actin and S-100. Shewas treated with left posterolateral thoracotomy with en bloc tumor resection. The tissue pathology showed solitaryfibrous tumors of the pleura with mitotic figure 0-1/50 HPF, no area of tumor necrosis and free surgical margin.The surgical treatment resulted in good outcome without post-operative complication.
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Thai Journal of Tuberculosis Chest Diseases and Critical Care; Vol.30 No.1 January-March 2009; 63-71