Steroid hormones retard aflatoxin-induced cytotoxicity.
| dc.contributor.author | Raval, P J | en_US |
| dc.contributor.author | Verma, R J | en_US |
| dc.date.accessioned | 2009-05-28T13:23:50Z | |
| dc.date.available | 2009-05-28T13:23:50Z | |
| dc.date.issued | 1993-09-01 | en_US |
| dc.description.abstract | Protective effect of sex steroid hormones on aflatoxin-induced cytotoxicity on RBC (hemolysis) was examined in vitro. Addition of aflatoxin (2 micrograms/ml) in RBC suspension caused significant increase in hemolysis. Concurrent addition of aflatoxin (2 micrograms/ml) and estradiolbenzoate (100-1200 pg/ml) in RBC suspension significantly retarded aflatoxin-induced hemolysis. Similarly, addition of aflatoxin (2 micrograms/ml) along with testosterone propionate (5-60 ng/ml) in RBC suspension retarded aflatoxin-induced hemolysis. Among the two synthetic hormones studied estradiolbenzoate was more potent than testosterone propionate. | en_US |
| dc.description.affiliation | Department of Life Sciences, Bhavnagar University, India. | en_US |
| dc.identifier.citation | Raval PJ, Verma RJ. Steroid hormones retard aflatoxin-induced cytotoxicity. Indian Journal of Experimental Biology. 1993 Sep; 31(9): 780-1 | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/59354 | |
| dc.language.iso | eng | en_US |
| dc.source.uri | https://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.asp | en_US |
| dc.subject.mesh | Adult | en_US |
| dc.subject.mesh | Aflatoxins --antagonists & inhibitors | en_US |
| dc.subject.mesh | Estradiol --analogs & derivatives | en_US |
| dc.subject.mesh | Hemolysis --drug effects | en_US |
| dc.subject.mesh | Humans | en_US |
| dc.subject.mesh | Testosterone --pharmacology | en_US |
| dc.title | Steroid hormones retard aflatoxin-induced cytotoxicity. | en_US |
| dc.type | In Vitro | en_US |
| dc.type | Journal Article | en_US |
| dc.type | Research Support, Non-U.S. Gov't | en_US |
Files
License bundle
1 - 1 of 1