Responses of serum calcium and inorganic phosphate levels, parathyroid gland and C cells of Rattus norvegicus to heptachlor administration.

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dc.contributor.authorRangoonwala, Shaheda Pen_US
dc.contributor.authorSuryawanshi, S Aen_US
dc.contributor.authorPandey, A Ken_US
dc.date.accessioned2004-01-12en_US
dc.date.accessioned2009-06-02T03:36:43Z
dc.date.available2004-01-12en_US
dc.date.available2009-06-02T03:36:43Z
dc.date.issued2004-01-12en_US
dc.description.abstractIntramuscular administration of two doses: 0.50 LD50 (14.70 mg/kg b w) and 0.75 LD50 (22.30 mg/kg b w) of heptachlor in Rattus norvegicus for 14 days induced significant hypocalcemia without altering serum inorganic phosphate value. Parathyroid chief cells of the experimental rats exhibited degranulation, vacuolation, loss of secretory granules and lipid droplets, reduction in chromatin, and degenerative changes in endoplasmic reticulum and cristae of the mitochondria. Not much of histological and ultrastructural changes could be seen in C cells of the heptachlor treated rats.en_US
dc.description.affiliationDepartment of Zoology, Institute of Science, 15 Madam Cama Road, Mumbai-400032, India.en_US
dc.identifier.citationRangoonwala SP, Suryawanshi SA, Pandey AK. Responses of serum calcium and inorganic phosphate levels, parathyroid gland and C cells of Rattus norvegicus to heptachlor administration. Journal of Environmental Biology. 2004 Jan; 25(1): 75-80en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/113186
dc.language.isoengen_US
dc.source.urihttps://www.geocities.com/j_environ_biol/en_US
dc.subject.meshAnimalsen_US
dc.subject.meshCalcium --blooden_US
dc.subject.meshChromatin --drug effectsen_US
dc.subject.meshCytoplasmic Granules --drug effectsen_US
dc.subject.meshEndoplasmic Reticulum --drug effectsen_US
dc.subject.meshGolgi Apparatus --drug effectsen_US
dc.subject.meshHeptachlor --administration & dosageen_US
dc.subject.meshLipidsen_US
dc.subject.meshMaleen_US
dc.subject.meshMitochondria --drug effectsen_US
dc.subject.meshParathyroid Glands --cytologyen_US
dc.subject.meshPhosphates --blooden_US
dc.subject.meshRatsen_US
dc.subject.meshSoil Pollutants --toxicityen_US
dc.titleResponses of serum calcium and inorganic phosphate levels, parathyroid gland and C cells of Rattus norvegicus to heptachlor administration.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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