Longitudinal follow-up of lymphocyte subsets during the first year of life.

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dc.contributor.authorTsao, Po-Nienen_US
dc.contributor.authorChiang, Bor-Luenen_US
dc.contributor.authorYang, Yao-Hsuen_US
dc.contributor.authorTsai, Ming-Jeren_US
dc.contributor.authorLu, Frank Len_US
dc.contributor.authorChou, Hung-Chienen_US
dc.contributor.authorTsou, Kuo-Innen_US
dc.date.accessioned2009-05-27T17:06:43Z
dc.date.available2009-05-27T17:06:43Z
dc.date.issued2002-09-18en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractA longitudinal study of lymphocyte subsets during infancy was evaluated by using the flow cytometric immunophenotyping method. Two hundred and thirteen blood samples were obtained from 92 healthy, full-term infants of the following ages: 1-7 days old (n = 43), 3 months old (n = 55), 6 months old (n = 57) and 11 months old (n = 58). The absolute numbers of CD3+ and CD3+/CD4+ T lymphocytes increased from birth to 3 months of age, and remained stable thereafter. The absolute number of CD3+/CD8+ T lymphocytes increased from birth to 11 months of age. The absolute number of CD19+ B lymphocytes and NK cells increased rapidly (3 months) after birth and continued to increase throughout the study period. However, the changes in the relative counts of lymphocyte subsets did not always correspond with the changes in their absolute numbers. These results demonstrate the age-related changes in lymphocyte subpopulations and provide reference ranges for lymphocyte subsets during infancy.en_US
dc.description.affiliationDepartment of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.en_US
dc.identifier.citationTsao PN, Chiang BL, Yang YH, Tsai MJ, Lu FL, Chou HC, Tsou KI. Longitudinal follow-up of lymphocyte subsets during the first year of life. Asian Pacific Journal of Allergy and Immunology. 2002 Sep; 20(3): 147-53en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36476
dc.language.isoengen_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAntigens, Differentiation, B-Lymphocyte --blooden_US
dc.subject.meshAntigens, Differentiation, T-Lymphocyte --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshGestational Ageen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant Welfareen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshKiller Cells, Natural --immunologyen_US
dc.subject.meshLongitudinal Studiesen_US
dc.subject.meshLymphocyte Counten_US
dc.subject.meshLymphocyte Subsets --immunologyen_US
dc.subject.meshMaleen_US
dc.subject.meshReference Valuesen_US
dc.subject.meshSex Factorsen_US
dc.subject.meshT-Lymphocytes --immunologyen_US
dc.subject.meshTaiwanen_US
dc.titleLongitudinal follow-up of lymphocyte subsets during the first year of life.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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