A model for cell type localization in the migrating slug of Dictyostelium discoideum based on differential chemotactic sensitivity to cAMP and differential sensitivity to suppression of chemotaxis by ammonia.

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dc.contributor.authorFeit, Ira Nen_US
dc.contributor.authorPawlikowski, Jeffreyen_US
dc.contributor.authorZawilski, Carolineen_US
dc.date.accessioned2007-03-17en_US
dc.date.accessioned2009-06-01T14:53:16Z
dc.date.available2007-03-17en_US
dc.date.available2009-06-01T14:53:16Z
dc.date.issued2007-03-17en_US
dc.description.abstractThe three basic cell types in the migrating slug of Dictyostelium discoideum show differential chemotactic response to cyclic AMP (cAMP) and differential sensitivity to suppression of the chemotaxis by ammonia.The values of these parameters indicate a progressive maturation of chemotactic properties during the transdifferentiation of slug cell types.We present a model that explains the localization of the three cell types within the slug based on these chemotactic differences and on the maturation of their chemotactic properties.en_US
dc.description.affiliationFranklin and Marshall College, Lancaster, PA 17603, USA. ifeit@fandm.eduen_US
dc.identifier.citationFeit IN, Pawlikowski J, Zawilski C. A model for cell type localization in the migrating slug of Dictyostelium discoideum based on differential chemotactic sensitivity to cAMP and differential sensitivity to suppression of chemotaxis by ammonia. Journal of Biosciences. 2007 Mar; 32(2): 329-38en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/111149
dc.language.isoengen_US
dc.source.urihttps://www.ias.ac.in/jbiosci/index.htmlen_US
dc.subject.meshAmmonia --toxicityen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCell Differentiation --physiologyen_US
dc.subject.meshChemotactic Factors --metabolismen_US
dc.subject.meshChemotaxis --drug effectsen_US
dc.subject.meshCyclic AMP --metabolismen_US
dc.subject.meshDictyostelium --cytologyen_US
dc.subject.meshModels, Biologicalen_US
dc.titleA model for cell type localization in the migrating slug of Dictyostelium discoideum based on differential chemotactic sensitivity to cAMP and differential sensitivity to suppression of chemotaxis by ammonia.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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