Spectrum of anemia in pregnant Indian women and importance of antenatal screening.

Simple item page
dc.contributor.authorSinha, Madhuen_US
dc.contributor.authorPanigrahi, Inushaen_US
dc.contributor.authorShukla, Jyotien_US
dc.contributor.authorKhanna, Anuradhaen_US
dc.contributor.authorSaxena, Renuen_US
dc.date.accessioned2006-07-28en_US
dc.date.accessioned2009-05-29T11:52:58Z
dc.date.available2006-07-28en_US
dc.date.available2009-05-29T11:52:58Z
dc.date.issued2006-07-28en_US
dc.description.abstractAnemia is a common health problem but control of anemia in pregnant women is less well studied. The purpose was to study prevalence of anemia in young pregnant women, correlate with indices and study significance of identification of hemoglobinopathies. Of the 120 pregnant women, Hb was less than 8 g% in 58 (44.2%). Seventy-eight (65%) had iron deficiency, 22 (18.3%) had dimorphic anemia, and 14 (11.6%) had hemolytic anemia. Megaloblastic anemia was present in 6 (5%). Of hemolytic anemia, 50% were thalassemia trait. MCV< 76 fl was observed in 88 (73.3 %) cases. MCV<76 fl and MCH < 27 pg had 100 % sensitivity and 28.7 % specificity for screening of beta-thalassemia trait. NESTROFT had comparable sensitivity but lower specificity (14.9%). Sixty-three percent (60/78) of IDA had increased RDW whereas 78 % (11/14) of hemolytic anemia had RDW value in normal range (p value< 0.05). MCV/RBC of <14 was more specific parameter (96.8%) for beta-thalassemia trait. Four high-risk couples were identified. Thus, moderate to severe anemia was observed in most pregnant women. Hemoglobinopathies should be screened in antenatal clinics to identify the couples that would need a prenatal test. A lower MCV/RBC with RDWin the normal range may be useful in screening for thalassemia trait in pregnant women.en_US
dc.description.affiliationDepartment of Pathology, Institute of Medical Sciences, BHU, Varanasi.en_US
dc.identifier.citationSinha M, Panigrahi I, Shukla J, Khanna A, Saxena R. Spectrum of anemia in pregnant Indian women and importance of antenatal screening. Indian Journal of Pathology & Microbiology. 2006 Jul; 49(3): 373-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73995
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAnemia --epidemiologyen_US
dc.subject.meshAnemia, Hemolytic --epidemiologyen_US
dc.subject.meshAnemia, Iron-Deficiency --epidemiologyen_US
dc.subject.meshAnemia, Megaloblastic --epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHematologic Testsen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMass Screeningen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Hematologic --epidemiologyen_US
dc.subject.meshPrenatal Diagnosisen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSickle Cell Trait --epidemiologyen_US
dc.titleSpectrum of anemia in pregnant Indian women and importance of antenatal screening.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Pathology & Microbiology