Ventilatory pulmonary function tests in type 1 diabetes mellitus.

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dc.contributor.authorMakkar, Pen_US
dc.contributor.authorGandhi, Men_US
dc.contributor.authorAgrawal, R Pen_US
dc.contributor.authorSabir, Men_US
dc.contributor.authorKothari, R Pen_US
dc.date.accessioned2000-10-24en_US
dc.date.accessioned2009-05-31T04:33:18Z
dc.date.available2000-10-24en_US
dc.date.available2009-05-31T04:33:18Z
dc.date.issued2000-10-24en_US
dc.description.abstractOBJECTIVE: To study the ventilatory pulmonary function tests (VPFT) in type one diabetes mellitus and to correlate it with duration, meticulous metabolic control and various complications of diabetes. METHODOLOGY: Spirometric evaluation of 50 young (15-30 years of age) type one diabetes mellitus patients was done under the case control longitudinal study. After recording baseline parameters patients were subjected to PFT. OBSERVATIONS: Degree of derangement in VPFTs was directly related to duration and metabolic control of diabetes. VPFT parameters such as FVC, FEV1, PEFR, MEF 75% and MEF 25% showed significant reduction (p = 0.009, = 0.001, = 0.001, = 0.05 respectively). Similarly patients with HbA1c > 10% showed significant reduction in FVC, FEV1, PEFR and MEF 75% (p = 0.001 for each). Diabetic patients with complications particularly peripheral neuropathy and nephropathy had significant reduction in FVC, FEV1 and PEFR (p = 0.001). CONCLUSION: Spirometric evaluation in type one diabetes mellitus showed varying derangements in the different parameters of VPFTs, suggestive of dominantly restrictive with some obstructive pattern as indicated by significant decline in FVC, PEFR and MEF 75%.en_US
dc.description.affiliationDepartment of Medicine, SP Medical College, Bikaner-334 003.en_US
dc.identifier.citationMakkar P, Gandhi M, Agrawal RP, Sabir M, Kothari RP. Ventilatory pulmonary function tests in type 1 diabetes mellitus. Journal of the Association of Physicians of India. 2000 Oct; 48(10): 962-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/94848
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshDiabetes Mellitus, Type 1 --diagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshLongitudinal Studiesen_US
dc.subject.meshMaleen_US
dc.subject.meshPrognosisen_US
dc.subject.meshReference Valuesen_US
dc.subject.meshRespiratory Function Testsen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshSpirometryen_US
dc.titleVentilatory pulmonary function tests in type 1 diabetes mellitus.en_US
dc.typeJournal Articleen_US
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