Effect of gamma irradiation on chemical and biological properties of lipopolysaccharide from Salmonella typhimurium.

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dc.contributor.authorNaidu, M Den_US
dc.contributor.authorChander, Ren_US
dc.contributor.authorNair, P Men_US
dc.date.accessioned2009-05-28T13:39:41Z
dc.date.available2009-05-28T13:39:41Z
dc.date.issued1998-06-10en_US
dc.description.abstractLipopolysaccharide (LPS) from S. typhimurium on exposure to gamma-radiation resulted in decrease in toxicity and was less mitogenic, Silver stained profiles of irradiated LPS on polyacrylamide gels revealed complete loss of its heteropolysaccharides which was confirmed further by analysing lipid A and LPS from Salmonella minnesota Re mutants on SDS-PAGE. Glucosamine and 2-keto 3-deoxy-octonate(Kdo) contents were significantly decreased on treatment. Lipid A obtained by removal of heteropolysaccharides from LPS was less toxic on exposure to gamma radiations.en_US
dc.description.affiliationFood Technology Division, Bhabha Atomic Research Centre, Mumbai, India.en_US
dc.identifier.citationNaidu MD, Chander R, Nair PM. Effect of gamma irradiation on chemical and biological properties of lipopolysaccharide from Salmonella typhimurium. Indian Journal of Experimental Biology. 1998 Jun; 36(6): 588-92en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/59701
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshGamma Raysen_US
dc.subject.meshLipopolysaccharides --chemistryen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, Inbred C57BLen_US
dc.subject.meshMitogens --pharmacologyen_US
dc.subject.meshSalmonella typhimurium --chemistryen_US
dc.subject.meshSpleen --cytologyen_US
dc.titleEffect of gamma irradiation on chemical and biological properties of lipopolysaccharide from Salmonella typhimurium.en_US
dc.typeJournal Articleen_US
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