Disseminated malignant fibrous histiocytoma (giant cell rich): a case report.

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dc.contributor.authorRao, Shalineeen_US
dc.contributor.authorArcot, Rekhaen_US
dc.contributor.authorPai, Vishwanathen_US
dc.contributor.authorPrathiba, Den_US
dc.date.accessioned2007-10-01en_US
dc.date.accessioned2009-05-29T11:42:34Z
dc.date.available2007-10-01en_US
dc.date.available2009-05-29T11:42:34Z
dc.date.issued2007-10-01en_US
dc.description.abstractGiant cell rich malignant fibrous histiocytoma accounts for 3 -15% of all malignant fibrous histiocytomas. Currently, the nomenclature giant cell malignant fibrous histiocytoma is reserved for undifferentiated pleomorphic sarcomas with prominent osteoclastic giant cells. It is considered to be synonymous with malignant giant cell tumor of soft parts. We report a case of disseminated giant cell malignant fibrous histiocytoma involving the scalp, cervical node, lungs, spine, abdominal wall, base of penis, gluteal cleft, paraspinal region and back. The diagnosis was established after staining for a panel of immunohistochemical markers namely cytokeratin, vimentin, S100, desmin, CD68 and smooth muscle actin. CD68 positivity in tumor cells helped in arriving at the final diagnosis. It is essential to recognize this tumor as a giant cell rich distinct entity and differentiate from other giant cell rich pleomorphic sarcomas since therapeutic and prognostic differences are being appreciated currently.en_US
dc.description.affiliationDepartment of Pathology, Sri Ramachandra Medical College and Research Institute, Chennai.en_US
dc.identifier.citationRao S, Arcot R, Pai V, Prathiba D. Disseminated malignant fibrous histiocytoma (giant cell rich): a case report. Indian Journal of Pathology & Microbiology. 2007 Oct; 50(4): 795-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73809
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAbdominal Wall --pathologyen_US
dc.subject.meshBack --pathologyen_US
dc.subject.meshGiant Cells --cytologyen_US
dc.subject.meshHistiocytoma, Malignant Fibrous --diagnosisen_US
dc.subject.meshHistocytochemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshLung --pathologyen_US
dc.subject.meshLymph Nodes --pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Metastasis --pathologyen_US
dc.subject.meshPenis --pathologyen_US
dc.subject.meshScalp --pathologyen_US
dc.subject.meshSpine --pathologyen_US
dc.subject.meshTumor Markers, Biologicalen_US
dc.titleDisseminated malignant fibrous histiocytoma (giant cell rich): a case report.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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