Comparison of Post-operative Analgesic Efficacy of Caudal Epidural Bupivacaine Versus Bupivacaine and Neostigmine Combination in Infraumbilical Surgeries in Children.

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dc.contributor.authorMaji, Sunanda
dc.contributor.authorRoy, Jaydeb
dc.contributor.authorGupta, Sampa Dutta
dc.contributor.authorBandhyopadhyay, Tibar
dc.contributor.authorKundu, Kanak Kanti
dc.date.accessioned2015-04-16T04:13:17Z
dc.date.available2015-04-16T04:13:17Z
dc.date.issued2013-05
dc.description.abstractSpinal muscarinic M1 receptors are believed to be involved in the analgesic properties of spinal neostigmine. Aims were to determine the effect of adding neostigmine to bupivacaine on the duration of caudal analgesia as compared with caudal bupivacaine alone, to determine the need for rescue analgesics in the post-operative period. Material and Methods: 50 patients of ASA Grade I and II, aged between 2 to 8 years, of either sex underwent infraumbilical surgeries. Post-operative caudal epidural analgesia was activated after completion of the surgery and before recovery from anaesthesia Group-A (n=25) received caudal epidural injection of preservative free bupivacaine 0.125%. 2 mg/kg, Group-B (n=25) received both preservative free bupivacaine 0.125% and neostigmine 2μg/kg. Results and Analysis: After extubation children were evaluated for pain using the CHEOPS pain scale, shows no significant difference between the two study groups at 2 post-operative hours. Group B patients required less rescue analgesic than Group A patients in 24 hrs postoperative period. Conclusion: Addition of neostigmine to bupivacaine in caudal epidural bupivacaine prolonged the duration of caudal analgesia in the post-operative period compared to caudal bupivacaine alone.en_US
dc.identifier.citationMaji Sunanda, Roy Jaydeb, Gupta Sampa Dutta, Bandhyopadhyay Tibar, Kundu Kanak Kanti. Comparison of Post-operative Analgesic Efficacy of Caudal Epidural Bupivacaine Versus Bupivacaine and Neostigmine Combination in Infraumbilical Surgeries in Children. Indian Medical Gazette. 2013 May ; 147 (5): 192-198.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/157512
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/ice/t13/i5/icet13i5p192.pdfen_US
dc.subjectcaudal epidural bupivacaineen_US
dc.subjectneostigmineen_US
dc.subjectpostoperative analgesiaen_US
dc.subject.meshAnalgesia, Epidural --methods
dc.subject.meshAnalgesics --administration & dosage
dc.subject.meshAnesthesia, Epidural --methods
dc.subject.meshAnesthesia, Caudal --methods
dc.subject.meshBupivacaine --administration & dosage
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshDrug Combinations
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshNeostigmine --administration & dosage
dc.subject.meshPain, Postoperative --drug therapy
dc.subject.meshUmbilicus --surgery
dc.titleComparison of Post-operative Analgesic Efficacy of Caudal Epidural Bupivacaine Versus Bupivacaine and Neostigmine Combination in Infraumbilical Surgeries in Children.en_US
dc.typeArticleen_US
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