Genetic epidemiology of the three predominant abnormal hemoglobins in India.

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Date
1996-01-01
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Abstract
Hemoglobinopathies in India are Important public health problems. Of the several abnormal of hemoglobin molecules, there are three variants, viz. Sickle cell, hemoglobin E and hemoglobin D which are predominantly prevalent in India. The cumulative gene frequencies of these hemoglobins have been found to be 5.35% in India. The average gene frequency of sickle cell and hemoglobin D in India has been observed to be 4.3% and 0.86%, respectively. In the North Eastern region of India, the gene frequency of hemoglobin E is 10.9%. Gene frequencies and spatial distribution of the predominant abnormal hemoglobins in India have been discussed in variance with the previous generalisations.
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Balgir RS. Genetic epidemiology of the three predominant abnormal hemoglobins in India. Journal of the Association of Physicians of India. 1996 Jan; 44(1): 25-8
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https://imsear.searo.who.int/handle/123456789/95582
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Journal of the Association of Physicians of India