Prognosis and management of membraneous nephropathy.
No Thumbnail Available
Date
1993-06-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Patients of idiopathic membranous nephropathy (MGN) were randomly assigned to received steroid and cyclophosphamide every other month (Gr-I) and steroid alone (Gr-II). Of 36 patients in Gr.I, 33 patients achieved complete remissions, 2 had relapsing course with remission on further courses of therapy and only one has reached end stage renal failure. In contrast, of the 35 patients in Gr. II, 15 (P < 0.001) achieved complete remission, 7 are in partial remission, 5 have no response, another 5 have deterioration of renal function of which two required dialysis, and 3 have relapsing course after the initial remission. Mean follow up period was 46 +/- 10.2 months. We conclude that steroid and cyclophosphamide every other month is highly effective in achieving remission in patients with membranous nephropathy.
Description
Keywords
Citation
Pahari DK, Das S, Dutta BN, Banerjee D. Prognosis and management of membraneous nephropathy. Journal of the Association of Physicians of India. 1993 Jun; 41(6): 350-1