Post heparin lipoprotein lipase activity in patients of ischaemic heart disease and in controls.
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1990-09-01
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A single high fat meal diet (66 gm fat) was given to 30 healthy males and 20 male patients of ischaemic heart disease (IHD). Ten minutes prior to the 4th postprandial hour, 500 units of heparin--a lipoprotein lipase (LPL) activator--was given, and its effect seen on serum triglyceride (STG) levels observed. Besides higher fasting STG levels, the decline in 4 hour post-prandial STG level was significantly lower in patients of IHD. One explanation for higher fasting STG values and prolonged postprandial lipaemia in these subjects could be deficient LPL activity.
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Arora RC, Agarwal N, Arora S, Kumar N, Lakhtakia S. Post heparin lipoprotein lipase activity in patients of ischaemic heart disease and in controls. Journal of the Association of Physicians of India. 1990 Sep; 38(9): 635