Myoglobinuria and transient acute renal failure in a patient revealing hypothyroidism.

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1999-04-25
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Muscle involvement in hypothyroidism commonly manifests as fatigue, myalgias, stiffness and slowed reflexes. We report a case of transient acute renal failure related to rhabdomyolysis and myoglobinuria in a 40 year old man that revealed the diagnosis of hypothyroidism with myopathy. The patient had proximal muscle weakness and tenderness, markedly raised muscle enzymes and deranged renal functions that normalised with thyroid replacement therapy. Hypothyroidism, though rare, should be considered a definite and authentic cause of rhabdomyolysis.
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Jain S, Bhargava K, Sawlani KK, Daga MK, Gaiha M. Myoglobinuria and transient acute renal failure in a patient revealing hypothyroidism. Journal of the Association of Physicians of India. 1999 Apr; 47(4): 444-6