Granulomatous angiitis of the central nervous system associated with herpes zoster.
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2002-07-20
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Abstract
Granulomatous angiitis of central nervous system (CNS) is a rare inflammatory disease of blood vessels mostly confined to CNS. We describe a case which presented with right sided hemiplegia with aphasia, after herpes zoster ophthalmicus. CT scan and MRI brain showed a large left sided infarct in the left middle cerebral artery (MCA) territory. MRI angiography revealed narrowing and thinning of left internal carotid artery (ICA) and to a lesser extent, left MCA suggestive of granulomatous vasculitis. Herpes zoster is often associated with major CNS involvement and a vascular etiology was previously postulated. Recent pathological reports suggest that cerebral angiitis secondary to herpes virus infection may be more common than realised.
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Bhat G, Mathur DS, Saxena GN, Jain S, Singh AP, Bhaduria D. Granulomatous angiitis of the central nervous system associated with herpes zoster. Journal of the Association of Physicians of India. 2002 Jul; 50(): 977-8