Coxsackie virus and rheumatic fever. A correlative study.
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1989-09-01
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Abstract
Twenty-one patients of whom 13 had acute rheumatic fever and 8 had recurrence of rheumatic fever were studied for the evidence of coxsackie B viral infection using neutralisation test. A significant rise was noted in 17 cases (81%) and two cases had very high initial titre of neutralising antibodies to coxsackie B viruses type 1 to 6. Mixed infection with more than one serotype was seen in 11 cases. Coxsackie B2 was the commonest type and 14 patients had antistreptolysin 'O' anti-bodies. The high incidence of coxsackie B viral infection in rheumatic fever and the coexistent streptococcal infection and their relationship are discussed.
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Suresh L, Chandrasekar S, Rao RS, Ravi V, Badrinath S. Coxsackie virus and rheumatic fever. A correlative study. Journal of the Association of Physicians of India. 1989 Sep; 37(9): 582-5