Progressive supranuclear palsy. Report of 14 cases with special reference to unusual features.
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1991-06-01
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Abstract
The clinical features and course of 14 patients with progressive supranuclear palsy (PSP) were analysed. PSP formed 2.3 percent of the parkinsonian population. Blepharospasm, hypersomnia, athetosis, action dystonia, action myoclonus and family history of dementia were the unusual features. Half of the patients had dementia at presentation. Drug therapy was uniformly disappointing. The mean duration from onset to death in 4 patients who died was 4.5 years. The histopathological features in a patient with the disease for one year and who died of acute myocardial infarction showed moderately severe changes characteristic of the disease.
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Suresh TG, Rao TV. Progressive supranuclear palsy. Report of 14 cases with special reference to unusual features. Journal of the Association of Physicians of India. 1991 Jun; 39(6): 471-5