Human leucocyte antigen and insulin dependent diabetes mellitus.
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1991-07-01
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Abstract
HLA typing was done in 25 cases of insulin dependent diabetes mellitus (IDDM) and compared with 60 healthy controls. There was a significantly increased frequency of HLA B-8, HLA B-12 and HLA DR-3 in IDDMO. The odds ratio (relative risk) of developing IDDM for HLA B-8 was 4.42 (p less than 0.10), for HLA B-12 was 3.56 (p less than 0.10) and for HLA DR3 9.75 (p less than 0.001). There was no correlation of HLA specificity with complications of diabetes.
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Gupta MM, Raghunath D, Kher SK, Radhakrishnan AP. Human leucocyte antigen and insulin dependent diabetes mellitus. Journal of the Association of Physicians of India. 1991 Jul; 39(7): 540-3