Analgesics for pediatric use.
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Date
2000-08-14
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Abstract
The use of nimesulide is increasing and recently, concerns have been raised regarding its hepatotoxicity, especially in children. At least two deaths due to fulminant hepatic failure have been attributed to nimesulide. In India, nimesulide has been approved and about twelve pediatric preparations are available. Lack of effective postmarketing surveillance means that adverse drug reactions may not be picked or reported. Therefore, quick approval of those drugs for which substitutes are available may not be desirable in India and in other developing countries.
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8 references.
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Malhotra S, Pandhi P. Analgesics for pediatric use. Indian Journal of Pediatrics. 2000 Aug; 67(8): 589-90