Pediatric HIV infection.
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2005-11-05
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Abstract
OBJECTIVE: The present cross sectional study was undertaken to study clinical profile of HIV infection in children in Northern India.
METHODS: 64 children from newborn to eighteen years, presenting for confirmation of diagnosis of HIV infection or monitoring of CD4-CD8 counts in confirmed cases, were evaluated. Children were categorized as per CDC classification of Pediatric HIV. The diagnosis was confirmed by serological tests or PCR assay. CD4-CD8 counts were done by FACS Count.
RESULTS: Majority of the children were between 18 months to 5 years. Adolescents comprised 24% of the case. 51.5% children were infected through the mode of mother to child transmission. 39% of the case was transfusion-mediated. Unsafe medical injections probably contributed to 6.2% and heterosexual promiscuity led to 3.1% cases. Clubbing, not described in Indian studies so far, was seen in 9.3% cases.
CONCLUSIONS: HIV infection is a chronic childhood disease extending into adolescence, and contaminated blood and unsafe medical injections are still important routes of HIV transmission in India.
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Sehgal R, Baveja UK, Chattopadhya D, Chandra J, Lal S. Pediatric HIV infection. Indian Journal of Pediatrics. 2005 Nov; 72(11): 925-30