Clinico-pathological profile of pediatric lymphadenopathy.
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2002-12-01
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Abstract
OBJECTIVE: To study the clinico-pathological profile of significant pediatric peripheral lymphadenopathy and to arrrive at an etiological diagnosis.
METHODS: Prospective study in a tertiary care hospital setting. One hundred consecutive children reporting to pediatric OPD from 1 January 1995 to 31 December 1998, aged 1 month to 12 years were studied.
RESULTS: The commonest aetiology diagnosed was tubercular lymphadenitis in 35% cases, followed by chronic tonsillopharyngitis in 15% cases. Lymphomas, AIDS and infectious mononucleosis constituted 3, 2 and 1 cases each. Aetiology could not be ascertained in 44 (44%) children even after detailed haematological, microbiological, radiological and serological investigations. FNAC's sensitivity and specificity as compared to 'gold standard of excision lymph node biopsy was 94% and 100% respectively.
CONCLUSION: Tubercular lymphadenitis was the commonest treatable entity of significant pediatric peripheral lymphadenopathy. A majority of the cases even after thorough evaluation, remained undiagnosed. FNAC as a diagnostic modality is almost as sensitive and as specific as excision lymph node biopsy when an adequate aspirate is examined by expert eyes.
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Reddy MP, Moorchung N, Chaudhary A. Clinico-pathological profile of pediatric lymphadenopathy. Indian Journal of Pediatrics. 2002 Dec; 69(12): 1047-51