Caffey disease with raised immunoglobulin levels and thrombocytosis.

Kumar, T Sathish; Scott, Julius Xavier; Mathew, Leni Grace

Caffey disease with raised immunoglobulin levels and thrombocytosis.

Date

2008-02-13

Authors

Kumar, T Sathish

Scott, Julius Xavier

Mathew, Leni Grace

Abstract

Infantile cortical hyperostosis (Caffey disease) is characterized by radiological evidence of cortical hyperostosis, soft tissue swellings, fever and irritability. We report a case of Caffey disease highlighting its presentation with thrombocytosis and high serum immunoglobulin level to alert physicians to use steroids cautiously in view of the known thrombocythemic effect of the drug. Raised Immunoglobulin also suggests that this syndrome could be infectious in origin.

Citation

Kumar TS, Scott JX, Mathew LG. Caffey disease with raised immunoglobulin levels and thrombocytosis. Indian Journal of Pediatrics. 2008 Feb; 75(2): 181-2