Circulating immune complexes in leukaemias and lymphomas.
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1992-03-01
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Abstract
Circulating immune complexes (ClC) were estimated in 78 patients of leukaemias and lymphomas by Clq deviation ELISA and PEG assay. In all leukaemias a significant elevation in ClC was seen at the time of first presentation. While in ALL a decrease occurred on therapy as partial or complete remission was achieved, no such fall was seen in AML or CML-BC when treated. ClC levels were much higher in non-Hodgkins lymphoma than in Hodgkins disease and showed a direct correlation with B symptoms and activity of the disease. The ClC levels were highest in null-ALL followed by those in common ALL and T-ALL. The mean duration of remission in patients of ALL without elevation in ClC was much longer than in those with ClC.
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Kishore J, Kumar R, Choudhry VP, Bhargava M. Circulating immune complexes in leukaemias and lymphomas. Indian Journal of Pediatrics. 1992 Mar-Apr; 59(2): 225-31