Immunoglobulin profile in mycetoma.
No Thumbnail Available
Date
1996-07-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Serum samples obtained from 25 patients of mycetoma caused by Madurella mycetomi in 18, Streptomyces somaliensis in 5, Streptomyces madurae and streptomyces palletierii from 1 each and also from 25 healthy controls were evaluated for immunoglobulins IgG, IgM and IgA by radial immunodiffusion method using tripartigen plates. All the three classes of immunoglobulins showed increased concentration in cases of mycetoma by M. mycetomi and S. pelletierii. The raised levels of IgG and IgM in cases of mycetoma caused by S. madurae and S. somaliensis where bones were involved, were not statistically significant. IgA was consistently high in all cases of mycetoma irrespective of causative agent and tissue involved. These alterations may possibly reflect relatively poor IgG and IgM response in individuals with extension of mycetoma lesion to bones.
Description
Keywords
Citation
Singhvi A, Joshi KR, Sharma JC, Vyas MC. Immunoglobulin profile in mycetoma. Indian Journal of Pathology & Microbiology. 1996 Jul; 39(3): 203-6