Combined occurrence of von Willebrand's disease and factor XIII deficiency: a case report.

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Date
2003-04-17
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Abstract
We report the case of a three year old female child with combined occurrence of von Willebrand's disease and factor XIII deficiency, an extremely rare combination. The patient presented with prolonged bleeding following cuts and wounds. Clot solubility test using 5M urea was positive. Platelet aggregation using ristocetin was reduced, which corrected on adding normal plasma. Aggregation with other agonists was normal. We discuss the clinico- hematological profile of the case. Only one such case has been reported in literature in the past to the best of our knowledge.
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Batra VV, Saxena R, Sharma LM, Kashyap R, Chaudhry VP. Combined occurrence of von Willebrand's disease and factor XIII deficiency: a case report. Indian Journal of Pathology & Microbiology. 2003 Apr; 46(2): 217-9
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https://imsear.searo.who.int/handle/123456789/75848
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Indian Journal of Pathology & Microbiology