Evaluation of HBsAg carrier rate in acute viral hepatitis and high risk individuals using RPHA and ELISA.
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1996-10-01
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Abstract
A total of 600 individuals including 500 cases of hepatitis and 100 individuals at high risk for developing hepatitis were screened for hepatitis B surface antigen (HBsAg) using reverse passive haemagglutination (RPHA) and enzyme linked immunosorbent assay (ELISA). HBsAg carrier rate in clinically diagnosed cases of hepatitis was 38% and 32.4% by RPHA and ELISA respectively. In high risk individuals, the carrier rate was 14% by RPHA and 11% by ELISA. Taking ELISA as gold standard, RPHA showed 5.33% false positivity and 0.33% false negativity. The over all correlation between RPHA and ELISA was to the tune of 82.66%.
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Korgaonkar A, Verenkar MP, Savio R, Pinto MJ, Singh I. Evaluation of HBsAg carrier rate in acute viral hepatitis and high risk individuals using RPHA and ELISA. Indian Journal of Pathology & Microbiology. 1996 Oct; 39(4): 277-80