Primary langerhans cell histiocytosis of the vulva: report of a case and brief review of the literature.

Pan, Zenggang; Sharma, Sanjeev; Sharma, Poonam

Primary langerhans cell histiocytosis of the vulva: report of a case and brief review of the literature.

Date

2009-01-13

Authors

Pan, Zenggang

Sharma, Sanjeev

Sharma, Poonam

Abstract

Primary Langerhans cell histiocytosis (LCH) of the vulva is rare. Fifteen cases of primary cutaneous vulvar LCH have been reported in English literature. We report an additional case of LCH confined to the vulva. In this article, we describe the clinical presentation, histopathology and immunohistochemistry findings of vulvar LCH that are helpful to both gynecologists and pathologists in the diagnosis of this entity. We briefly discuss the pathogenesis of LCH. The debate whether LCH is a reactive or neoplastic entity is still ongoing.

Citation

Pan Z, Sharma S, Sharma P. Primary langerhans cell histiocytosis of the vulva: report of a case and brief review of the literature. Indian Journal of Pathology & Microbiology. 2009 Jan-Mar; 52(1): 65-8