Wilms' tumour : a clinicopathologic study with special reference to its morphologic variants.

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1995-01-01
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Twenty five cases of Wilms' tumour were studied with special reference to their morphological variations. Wilms' tumour constituted 7.6% of all the malignant tumours of childhood and 50% of renal malignancies. Male/female ratio was 4:1; the mean age being 3.5 years. Left side was commonly involved (60.9%) center dot bilateral involvement in one case (4.3%). Morphologic study revealed triphasic pattern in 60% cases, biphasic (epithelial + stromal) in 12% and monophasic pattern in 28%. Other features observed were myxomatous degeneration, rhabdomyoblasts, calcification and squamous epithelial pearls seen in 20%, 12%, 8% and 4% respectively.
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Sharma S, Nath P, Srivastava AN, Singh KM. Wilms' tumour : a clinicopathologic study with special reference to its morphologic variants. Indian Journal of Pathology & Microbiology. 1995 Jan; 38(1): 55-62