C-reactive proteins as an indicator of sub-clinical infection in cases of premature rupture of membranes.
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2003-07-18
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The present study was conducted on 25 cases of preterm, premature rupture of membranes and 25 patients preterm with intact membranes, between 28-36 weeks of gestation, admitted in the maternity ward of Obstetrics and Gynecology, PGIMS, Rohtak. The sensitivity and specificity of CRP determination was found to be 80% each as an early predictor of subclinical chorioamnionitis. TLC had a low sensitivity of 20% and specificity of 60% in detecting histopathological chorioamnionitis. So CRP estimation is a reliable marker for detection of early choriamnionitis, at the same time, it is quite affordable and reasonably simple.
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Saini S, Goel N, Sharma M, Arora B, Garg N. C-reactive proteins as an indicator of sub-clinical infection in cases of premature rupture of membranes. Indian Journal of Pathology & Microbiology. 2003 Jul; 46(3): 515-6