Nucleolar organizer regions in pituitary adenomas.

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Date
1995-01-01
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Abstract
In this study, thirty-two non-functional and eighteen functional pituitary adenomas were analysed for the presence of argyrophilic nucleolar organizer regions (Ag-NORs) in paraffin sections, using an one-step silver-colloidal staining method. Differences in the mean Ag-NOR numbers of functional pituitary adenomas were statistically significant than those of non-functional pituitary adenomas. It is being emphasised that evaluation of Ag-NOR count is a more reliable index than the presence of mitotic figures in predicting the proliferative activity as well as possibility of recurrence in a patient with pituitary adenoma.
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Radhakrishnan VV, Radhakrishnan NS, Misra BK, Rout D. Nucleolar organizer regions in pituitary adenomas. Indian Journal of Pathology & Microbiology. 1995 Jan; 38(1): 25-32
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https://imsear.searo.who.int/handle/123456789/72771
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Indian Journal of Pathology & Microbiology