Atypicality in presentation of neuroleptic malignant syndrome caused by olanzapine.

Mishra, Biswaranjan; Mishra, Baikunthanath; Sahoo, Saddichha; Arora, Manu; Khess, C R J

Atypicality in presentation of neuroleptic malignant syndrome caused by olanzapine.

Date

2007-10-13

Authors

Mishra, Biswaranjan

Mishra, Baikunthanath

Sahoo, Saddichha

Arora, Manu

Khess, C R J

Abstract

Neuroleptic malignant syndrome (NMS) is the most serious of acute neurological side effects produced by antipsychotic medication, characterized by hyperthermia, rigidity, altered consciousness and autonomic dysfunction, the prevalence of which varies from 0.4-1.4%. NMS is usually seen in treatment with high potency typical antipsychotics and very rarely with atypical antipsychotics. However, NMS cases have been reported with risperidone, clozapine, olanzapine and quetiapine. The presentations of NMS have often varied and we report another atypicality in presentation of NMS due to olanzapine use.

Citation

Mishra B, Mishra B, Sahoo S, Arora M, Khess CR. Atypicality in presentation of neuroleptic malignant syndrome caused by olanzapine. Indian Journal of Medical Sciences. 2007 Oct; 61(10): 570-3