Portal hypertension secondary to Langerhans cell histiocytosis.

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2001-09-26
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Abstract
We report two children, aged 2 and 2 1/2 years, with multisystem Langerhans cell histiocytosis (LCH). Both were administered chemotherapy, with apparently good response. However, hepatic fibrosis and portal hypertension were detected 5 and 1 1/2 years after therapy, respectively. The first child died after a bout of hematemesis. Hepatic fibrosis can proceed despite apparently successful chemotherapy in LCH.
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Bansal D, Marwaha RK, Trehan A, Poddar U, Radotra BD. Portal hypertension secondary to Langerhans cell histiocytosis. Indian Journal of Gastroenterology. 2001 Sep-Oct; 20(5): 201-2