Cobalamine deficiency associated with neuropathy and oral mucosal melanosis in untreated gluten-sensitive enteropathy.

Somay, Göksel; Cevik, Deniz Mataraci; Halaç, Gülistan Usak; Abut, Evren; Erenoglu, Nuri Yasar

Cobalamine deficiency associated with neuropathy and oral mucosal melanosis in untreated gluten-sensitive enteropathy.

Date

2005-05-26

Authors

Somay, Göksel

Cevik, Deniz Mataraci

Halaç, Gülistan Usak

Abut, Evren

Erenoglu, Nuri Yasar

Abstract

A 32-year-old woman was admitted with complaints of difficulty in walking and hypoaesthesia and tingling in her legs. She had short stature and brown-black hyperpigmentation, cheliosis, dental irregularities and scars in the axillary regions. Neurological examination revealed mild, symmetric, predominantly distal weakness of the legs; deep tendon reflexes were depressed. There was glove-and-stocking decrease in pinprick and temperature perception but proprioception and light touch were normal. Investigations established a diagnosis of celiac disease; her neurological features improved on gluten-free diet, but oral pigmentation persisted.

Citation

Somay G, Cevik DM, Halaç GU, Abut E, Erenoglu NY. Cobalamine deficiency associated with neuropathy and oral mucosal melanosis in untreated gluten-sensitive enteropathy. Indian Journal of Gastroenterology. 2005 May-Jun; 24(3): 120-2