Infliximab in the treatment of ulcerative colitis with toxic megacolon.

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Date
2004-01-27
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Abstract
Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.
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Sriram PV, Reddy KS, Rao GV, Santosh D, Reddy DN. Infliximab in the treatment of ulcerative colitis with toxic megacolon. Indian Journal of Gastroenterology. 2004 Jan-Feb; 23(1): 22-3
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https://imsear.searo.who.int/handle/123456789/65170
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Indian Journal of Gastroenterology