Acral and palmo-plantar hyperpigmentation in a patient with disseminated hepatocellular carcinoma.

Abstract
Capecitabine (5-fluorouracil prodrug) is being evaluated for the management of hepatocellular carcinoma, and is associated with a peculiar skin reaction called hand and foot syndrome (HFS). We describe one patient with HCC and drug-induced HFS.
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Citation
Goyal R, Chalamalasetty SB, Madan K, Paul SB, Arora R, Safaya R, Acharya SK. Acral and palmo-plantar hyperpigmentation in a patient with disseminated hepatocellular carcinoma. Indian Journal of Gastroenterology. 2007 Nov-Dec; 26(6): 292-3