Effect of styrene on testicular enzymes of growing rat.
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1992-05-01
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Abstract
Effect of styrene (100 or 200 mg/kg body wt/day) for 60 days was observed on testicular enzymes of postnatally maturing rats. A significant decrease in epididymal spermatozoa count was observed only at 200 mg/kg body weight dose. Activities of testicular sorbitol dehydrogenase and acid phosphatase decreased while activities of lactate dehydrogenase, beta-glucuronidase, glucose-6-phosphate dehydrogenase, and gamma-glutamyl transpeptidase significantly increased only in animals exposed to styrene at a dose of 200 mg/kg body weight. The results suggest that exposure to high dose of styrene during developmental period alters the activities of enzymes associated with specific cell type of testis.
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Srivastava S, Seth PK, Srivastava SP. Effect of styrene on testicular enzymes of growing rat. Indian Journal of Experimental Biology. 1992 May; 30(5): 399-401