Detection of antibodies to serum IgA and IgG in peptic ulcer cases by indirect haemagglutination test.
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1993-09-01
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Autoantibodies to serum IgA and IgG were detected in 206 peptic ulcer patients (196 duodenal ulcer and 10 gastric ulcer) and 52 healthy age and sex-matched controls by indirect haemagglutination test. A significantly increased mean titre of autoantibodies to serum IgA was observed in the peptic ulcer patients. Forty-eight (24.61%) duodenal ulcer cases had autoantibody titre values above mean +/- 2 SD of controls. Titres of autoantibodies to serum IgG were significantly increased only in the gastric ulcer cases. The results suggest an immunologic abnormality in a sizeable fraction of these cases.
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Begum S, Ishaq M, Habibullah CM. Detection of antibodies to serum IgA and IgG in peptic ulcer cases by indirect haemagglutination test. Indian Journal of Experimental Biology. 1993 Sep; 31(9): 772-3