Effect of in utero exposure to di(2-ethylhexyl)phthalate on rat testes.

No Thumbnail Available
Date
1991-11-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
In utero exposure to di(2-ethylhexyl)phthalate (DEHP; 1000 mg/kg body weight) significantly decreased activities of testicular sorbitol dehydrogenase and acid phosphatase and increased gamma-glutamyl transpeptidase, lactate dehydrogenase and beta-glucuronidase activities at early ages. A decrease in the sperm count of the epididymal spermatozoa was also observed in the sexually matured animals of DEHP exposed group. The data suggest that in utero exposure to DEHP may affect the normal development of testes.
Description
Keywords
Citation
Tandon R, Seth PK, Srivastava SP. Effect of in utero exposure to di(2-ethylhexyl)phthalate on rat testes. Indian Journal of Experimental Biology. 1991 Nov; 29(11): 1044-6