Rapid detection of chemical carcinogens by measuring RNA released from microsomes in post-mitochondrial supernatant.

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Date
1996-06-01
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Abstract
Incubation of carcinogens with post-mitochondrial supernatant (PMS) and NADPH releases ribosomes from microsomes resulting in increased RNA concentration in post-microsomal supernatant. However, non-carcinogens fail to do so. Enhanced concentration of RNA in test over control samples can provide a useful index for the carcinogenicity of environmental pollutants.
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Dhanda JS, Dani HM, Sharma R. Rapid detection of chemical carcinogens by measuring RNA released from microsomes in post-mitochondrial supernatant. Indian Journal of Experimental Biology. 1996 Jun; 34(6): 597-9
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https://imsear.searo.who.int/handle/123456789/62509
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Indian Journal of Experimental Biology