In vitro antiviral activity of plant extracts on goatpox virus replication.
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2008-02-14
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Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro.
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Bhanuprakash V, Hosamani M, Balamurugan V, Gandhale P, Naresh R, Swarup D, Singh RK. In vitro antiviral activity of plant extracts on goatpox virus replication. Indian Journal of Experimental Biology. 2008 Feb; 46(2): 120-7