Hepatoprotective activity of Haridradi ghrita on carbon tetrachloride-induced liver damage in rats.
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2003-12-24
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Haridradi ghrita, a ghee based polyherbal formulation, (50, 100, 200 and 300 mg/kg) significantly lowered marker enzymes (SGPT, SGOT, ALP) and bilirubin in serum and liver peroxide, superoxide dismutase and catalase in liver homogenate following CCl4 (0.7 ml/kg, ip) toxicity. The protective effect was further supported by reversal of CCl4 induced histological changes. The results demonstrate significant hepatoprotective action of H. ghrita in CCl4 damaged rats.
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Satturwar PM, Fulzele SV, Joshi SB, Dorle AK. Hepatoprotective activity of Haridradi ghrita on carbon tetrachloride-induced liver damage in rats. Indian Journal of Experimental Biology. 2003 Dec; 41(12): 1447-51