Polyamines in inflammation and their modulation by conventional anti-inflammatory drugs.
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2007-07-08
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Abstract
Significant increase in polyamines levels in inflamed tissue was observed in the experimental animal models of inflammation. Treatment with dexamethasone positively modulated the levels of polyamines whereas non-steroidal drugs, diclofenac and valdecoxib negatively modulated their levels.
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Chakradhar LV, Naik SR. Polyamines in inflammation and their modulation by conventional anti-inflammatory drugs. Indian Journal of Experimental Biology. 2007 Jul; 45(7): 649-53